Table 2.

Meta-analysis results of the association between IL-10 -1082A/G, -592C/A, and -819T/C polymorphisms and lung cancer risk

IL-10	Allele model		Homozygous model		Dominant model		Recessive model
	OR/95% CI	P-value	OR/95% CI	P-value	OR/95% CI	P-value	OR/95% CI	P-value
A-1082G	A vs G		AA vs GG		AA vs (AG + GG)		(AA + AG) vs GG
Caucasians	1.37 (0.98–1.35)	0.08	1.33 (0.97–1.83)	0.08	1.21 (0.94–1.55)	0.14	1.21 (0.92–1.58)	0.17
Asians	1.14 (0.96–1.36)	0.14	0.99 (0.65–1.51)	0.95	1.20 (1.05–1.39)	<0.05	1.15 (0.92–1.43)	0.21
NSCLC	1.02 (0.89–1.18)	0.75	1.01 (0.77–1.33)	0.95	1.05 (0.87–1.27)	0.58	0.98 (0.76–1.27)	0.87
Total	1.17 (1.04–1.30)	<0.05	1.23 (0.98–1.54)	0.07	1.21 (1.05–1.40)	<0.05	1.15 (0.92–1.43)	0.21
C-592A	C vs A		CC vs AA		CC vs (CA + AA)		(CC + CA) vs AA
Caucasians	0.96 (0.83–1.11)	0.55	0.88 (0.59–1.33)	0.55	0.96 (0.80–1.14)	0.62	0.89 (0.60–1.34)	0.58
Asians	1.36 (1.20–1.53)	<0.05	1.85 (1.45–2.37)	<0.05	1.36 (1.15–1.61)	<0.05	0.74 (0.62–0.87)	<0.05
NSCLC	0.98 (0.87–1.10)	0.70	0.96 (0.77–1.21)	0.74	0.98 (0.84–1.14)	0.75	0.97 (0.79–1.20)	0.79
Total	0.84 (0.77–0.91)	<0.05	0.74 (0.64–0.87)	<0.05	0.83 (0.74–0.94)	<0.05	0.79 (0.69–0.91)	<0.05
T-819C	T vs C		TT vs CC		TT vs (TC + CC)		(TT + TC) vs CC
Caucasians	0.96 (0.65–1.41)	0.82	1.36 (0.44–4.17)	0.59	1.50 (0.50–4.50)	0.47	0.85 (0.53–1.38)	0.52
Asians	1.21 (1.06–1.38)	<0.05	1.54 (1.18–2.01)	<0.05	1.15 (0.97–1.37)	0.11	1.51 (1.17–1.95)	<0.05
NSCLC	1.57 (1.15–2.16)	<0.05	3.15 (1.58–6.30)	<0.05	1.37 (0.90–2.09)	0.14	3.07 (1.58–5.93)	<0.05
Total	0.97 (0.86–1.10)	0.63	0.95 (0.76–1.20)	0.68	0.96 (0.82–1.14)	0.66	0.97 (0.79–1.19)	0.77

Abbreviations: NSCLC, non-small-cell lung cancer; OR, odds ratio; 95% CI, 95% confidence interval.