Table II.
Structural parameters of cartilage and subchondral bone at different OA stages (mean ± SD).
| Groups | Mankin | TAC (µm) | SCP (µm) | BV/TV (%) |
|---|---|---|---|---|
| Early stage (n=15) | 3.3±1.2 | 2343.5±434.8 | 218.4±56.3 | 21.9±6.4 |
| Intermediate stage (n=13) | 7.7±0.9 | 1158.2±477.8a | 433.4±208.9a | 35.3±12.2a |
| Late stage (n=17) | 13.0±1.2 | 154.4±40.5a,b | 1223.2±291.4a,b | 49.7±5.0a,b |
a
P<0.05 vs. early stage;
b
P<0.05 vs. intermediate stage. OA, osteoarthritis; TAC, total articular cartilage; SCP, subchondral bone plate; BV/TV, trabecular bone volume.