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. 2016 Sep 30;38(5):1433–1442. doi: 10.3892/ijmm.2016.2763

Figure 3.

Figure 3

The spinal expression of p-c-Jun N-terminal kinase (JNK), phosphodiesterase 4B (PDE4B), glial fibrillary acidic protein (GFAP) and ionized calcium binding adapter molecule-1 (IBA-1) was inhibited by the intrathecal administration of rolipram (ROL). (A) Western blots showing the protein levels of p-JNK, PDE4B, GFAP and IBA-1. (B-E) Semi-quantitative assessment of the protein expression of p-JNK, PDE4B, GFAP and IBA-1 follwing ROL administration. Tissues were collected 14 days followig inoculation. **p<0.01; n.s., no significance; BCP, bone cancer pain; Veh, vehicle; Sham, sham-operated. Four rats were included in each group.