Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Sep 30;38(5):1433–1442. doi: 10.3892/ijmm.2016.2763

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Guo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Co-administration of rolipram (ROL) and SP600125 attenuates thermal hyperalgesia and chemokine (C-C motif) ligand 2 (CCL2) expression in rats with bone cancer pain (BCP). The intrathecal administration of SP600125 significantly attenuated thermal hyperalgesia compared with the vehicle control. The co-administration of ROL and SP600125 did not exert more potent effects on (A) paw withdrawal latency and (B) CCL2 expression compared to the administration of ROL alone. Tissues were collected 20 days following inoculation. ^**p<0.01; n.s., no significance; Veh, vehicle; Sham, sham-operated; SP, SP600125. Four rats were included in each group.