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. 2015 Nov 4;90(11):2763–2777. doi: 10.1007/s00204-015-1623-5

Table 4.

Long-term up-regulated genes enriched GO categories and pathways

Components Gene count p value Representative genes
GO term
 GO:0006917—induction of apoptosis 5 0.0030 TNFRSF10A, CDKN1A, ZMAT3, RRM2B, FAS
 GO:0033554—cellular response to stress 6 0.0039 XRCC4, CDKN1A, ZMAT3, RRM2B, NEFL, ETV5
 GO:0006974—response to DNA damage stimulus 4 0.0338 XRCC4, CDKN1A, ZMAT3, RRM2B
KEGG pathways
 hsa04115:p53 signalling pathway 5 4.7E−05 CDKN1A, ZMAT3, MDM2, RRM2B, FAS