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. 2015 Nov 2;90(11):2745–2761. doi: 10.1007/s00204-015-1621-7

Table 1.

Categorization of the 95 selected genes in distinct signaling pathways and cellular processes

Reference genes Transcription factors DNA damage response and repair Apoptosis Proliferation and cell cycle control Oxidative stress response Xenobiotic metabolism
ACTB AXIN2 APEX1 APAF1 CCND1 CAT ABCB1
B2M  BTRC ATM BAX CDKN1A FTH1 ABCC1
GAPDH JUN ATR BBC3 CDKN1B G6PD ADH1B
GUSB KEAP1 BRAC1/BRCA2 BCL2 CDKN2B GCLC ALDH1A1
HPRT1 MAP3K5 DDB1/DDB2 BCL2L1 E2F1 GPX1 CYP1A1
MDM2 DDIT3 PMAIP1 EGFR GPX2 EPHX1
NFE2L2 ERCC1/ERCC2 TNFRSF10B IL8 GSR GSTP1
NFKB1 ERCC4/ERCC5 XIAP MYC HMOX1 NAT1
NFKB2 GADD45A PLK3 HSPA1A NQO1
NFKBIA LIG1/LIG3 PPM1D MT1X SULT1A1
TP53 MGMT SIRT2 MT2A UGT1A
SLC30A1 MLH1 PRDX1
VEGFA MSH2 SEPP1
OGG1 SOD1
PARP1 SOD2
PCNA TFRC
POLB TXN1
POLD1 TXNRD1
RAD50/RAD51
RRM2B
XPA/XPC
XRCC5