Table 1.
Categorization of the 95 selected genes in distinct signaling pathways and cellular processes
| Reference genes | Transcription factors | DNA damage response and repair | Apoptosis | Proliferation and cell cycle control | Oxidative stress response | Xenobiotic metabolism |
|---|---|---|---|---|---|---|
| ACTB | AXIN2 | APEX1 | APAF1 | CCND1 | CAT | ABCB1 |
| B2M | BTRC | ATM | BAX | CDKN1A | FTH1 | ABCC1 |
| GAPDH | JUN | ATR | BBC3 | CDKN1B | G6PD | ADH1B |
| GUSB | KEAP1 | BRAC1/BRCA2 | BCL2 | CDKN2B | GCLC | ALDH1A1 |
| HPRT1 | MAP3K5 | DDB1/DDB2 | BCL2L1 | E2F1 | GPX1 | CYP1A1 |
| MDM2 | DDIT3 | PMAIP1 | EGFR | GPX2 | EPHX1 | |
| NFE2L2 | ERCC1/ERCC2 | TNFRSF10B | IL8 | GSR | GSTP1 | |
| NFKB1 | ERCC4/ERCC5 | XIAP | MYC | HMOX1 | NAT1 | |
| NFKB2 | GADD45A | PLK3 | HSPA1A | NQO1 | ||
| NFKBIA | LIG1/LIG3 | PPM1D | MT1X | SULT1A1 | ||
| TP53 | MGMT | SIRT2 | MT2A | UGT1A | ||
| SLC30A1 | MLH1 | PRDX1 | ||||
| VEGFA | MSH2 | SEPP1 | ||||
| OGG1 | SOD1 | |||||
| PARP1 | SOD2 | |||||
| PCNA | TFRC | |||||
| POLB | TXN1 | |||||
| POLD1 | TXNRD1 | |||||
| RAD50/RAD51 | ||||||
| RRM2B | ||||||
| XPA/XPC | ||||||
| XRCC5 |