Table 2.

Outcome for patients with ER positive tumors divided by PgR (IHC) status

Tam vs. control	PgR (IHC)	Number of patients/events		HR (95 % CI)	p value	P for interaction
		TAM	Control
Recurrence rate	All	329/70	289/102	0.54 (0.40–0.74)	<0.001	0.03
	≥10 %	225/43	182/72	0.43 (0.29–0.62)	<0.001
	<10 %	104/27	107/30	0.87 (0.52–1.46)	0.59
Distant recurrence rate	All	329/51	289/79	0.54 (0.38–0.76)	0.001	0.17
	≥10 %	225/31	182/53	0.45 (0.29–0.70)	<0.001
	<10 %	104/20	107/26	0.75 (0.42–1.34)	0.33
Breast cancer specific mortality rate	All	329/43	289/72	0.51 (0.35–0.74)	<0.001	0.33
	≥10 %	225/26	182/47	0.44 (0.27–0.71)	0.001
	<10 %	104/17	107/25	0.65 (0.35–1.21)	0.17