Table 3.
Outcome for patients with ER positive tumors divided by PgR (IHC) status and different time periods
| Tam vs. control | PgR (IHC) | 0–5 years | Beyond 5 years | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Number of patients/events | HR (95 % CI) | p value | Number of patients/events | HR (95 % CI) | p value | ||||
| TAM | Control | TAM | Control | ||||||
| Recurrence rate | All | 329/18 | 289/48 | 0.31 (0.18–0.53) | <0.001 | 294/52 | 228/54 | 0.74 (0.51–1.09) | 0.13 |
| ≥10 % | 225/12 | 182/33 | 0.27 (0.14–0.53) | <0.001 | 199/31 | 143/39 | 0.55 (0.34–0.88) | 0.012 | |
| <10 % | 104/6 | 107/15 | 0.39 (0.15–1.00) | 0.051 | 95/21 | 85/15 | 1.34 (0.69–2.60) | 0.39 | |
| Breast cancer specific mortality rate | All | 329/7 | 289/14 | 0.43 (0.18–1.08) | 0.072 | 305/36 | 265/58 | 0.53 (0.35–0.80) | 0.002 |
| ≥10 % | 225/3 | 182/9 | 0.27 (0.07–0.99) | 0.049 | 208/23 | 169/38 | 0.48 (0.29–0.81) | 0.006 | |
| <10 % | 104/4 | 107/5 | 0.81 (0.22–3.00) | 0.75 | 97/13 | 96/20 | 0.61 (0.31–1.24) | 0.17 | |