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Cumulative incidence of (a) biochemical failure, (b) distant metastasis, (c) prostate cancer-specific mortality, and (d) overall mortality. Estimates for biochemical failure, distant metastasis, and prostate cancer-specific mortality were calculated using the competing risk method, while estimates for overall mortality were compared using the Kaplan-Meier method. Red curves represent men with very-high-risk (VHR) disease. Blue curves represent other NCCN high-risk men.
