The BMM alters miRNA biogenesis protein expression in ALL. Drosha, Dicer, and Ago-1 protein abundance was measured in Nalm-27 and REH ALL cells in media only or co-cultured with BMSC or HOB by western blot. GAPDH was used as loading control. The western blots are representative images of 3 independent experiments. M, media; B, BMSC; H, HOB.