Table 2.
Compounds | A | B | C | D | E | F | G | H | |
---|---|---|---|---|---|---|---|---|---|
DENV 1 Pro | IC50 | 9.65 ±0.32 | 11.29±0.33 | 4.06±0.21 | 10.83±0.37 | 6.20±1.20 | 1.15±0.1 | 0.77±0.05 | 2.76±0.25 |
Hill-slope | 2.01±0.16 | 1.55±0.10 | 1.51±0.18 | 3.92±0.27 | 0.71±0.13 | 1.26±0.10 | 1.79±0.09 | 0.92±0.05 | |
DENV 2 Pro | IC50 | 8.22±0.24 | 10.01±0.28 | 4.05±0.18 | 10.45±0.40 | 4.84 ± 0.60 | 0.98±0.06 | 0.56±0.04 | 2.66±0.19 |
Hill-Slope | 1.79±0.11 | 2.21±0.18 | 1.61±0.18 | 2.75±0.16 | 1.11±0.16 | 1.51±0.07 | 1.60±0.07 | 0.97±0.04 | |
DENV 3 Pro | IC50 | 9.95±0.45 | 9.66±0.63 | 2.94±0.18 | 11.14±0.38 | 5.0±1.40 | 0.91±0.06 | 0.40±0.03 | 3.25±0.18 |
Hill-slope | 1.62±0.15 | 1.33±0.17 | 0.95±0.09 | 2.70±0.13 | 1.03±0.16 | 1.60±0.08 | 1.53±0.06 | 1.05±0.04 | |
DENV 4 Pro | IC50 | 8.95±0.34 | 12.20±0.47 | 3.40±0.11 | 11.04±0.37 | 5.32±0.60 | 0.64±0.03 | 0.13±0.01 | 3.73±0.14 |
Hill-slope | 2.22±0.21 | 1.95±0.19 | 1.53±0.12 | 3.20±0.16 | 1.22±0.13 | 1.45±0.05 | 0.79±0.03 | 1.25±0.12 | |
WNV Pro | IC50 | 6.43±0.38 | 10.06±0.33 | 2.53±0.10 | 6.56±0.24 | 4.31 ± 0.17 | 0.70±0.04 | 0.12±0.01 | 3.24±0.11 |
Hill-slope | 1.63±0.18 | 1.92±0.18 | 1.38±0.22 | 2.64±0.13 | 1.12±0.11 | 1.58±0.05 | 0.88±0.05 | 1.29±0.03 |
Values presented here are averages of duplicate experiments and reported with the standard errors of the mean.