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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Ocul Surf. 2016 Jul 30;14(4):419–434. doi: 10.1016/j.jtos.2016.06.003

Figure 1. Contact lens-induced limbal stem cell deficiency.

Figure 1

A. Early involvement of the superior cornea. There is whorl-like epithelium (red arrow) adjacent to an area of punctate staining (yellow area), which is the earliest sign of LSCD. B Superior involvement of the cornea, characteristic of moderate CL-induced LSCD. C. Late-staining fluorescein diffusely in a whorled pattern as a confluent sheet across the cornea in late-stage CL-induced LSCD. D. Characteristic superior involvement of corneal epithelium.