Table 3. 20-HETE, DiHETE and EETs levels according to different genotype combinations in patients and controls.
Stroke patients combination of rs17110453CC, rs751141GG, and rs9333025GG (n = 36) | Stroke patients other genotype combination (n = 187) | Controls combination of rs17110453CC, rs751141GG, and rs9333025GG (n = 16) | Controls other genotype combination (n = 110) | |
---|---|---|---|---|
20-HETE (pmol/L) | 1756 ± 172†‡ | 1452 ± 161 | 1521 ± 126 | 1396 ± 111 |
DiHETEs (nmol/l) | 84.23 ± 5.21†‡ | 71.72 ± 4.56 | 72.62 ± 4.73 | 68.98 ± 4.54 |
EETs (nmol/l) | 60.65 ± 4.27†‡ | 73.72 ± 5.13 | 70.87 ± 4.56 | 75.55 ± 5.01 |
HETE, hydroxyeicosatetraenoic acid; DiHETEs, dihydroxyeicosatrienoic acids; EET, epoxyeicosatrienoic acids.
P < 0.001, compared with controls with the genotype combination of rs17110453CC, rs751141GG, and rs9333025GG.
P < 0.001, compared with stroke patients with other genotype combination.