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. 2016 Oct 17;10:193. doi: 10.3389/fnbeh.2016.00193

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Copyright © 2016 del Hoyo, Xicota, Langohr, Sánchez-Benavides, de Sola, Cuenca-Royo, Rodriguez, Rodríguez-Morató, Farré, Dierssen, de la Torre and the TESDAD Study Group.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cognitive and functional performance associated to COMTVal158Met polymorphisms. Box plots represent the behavioral and cognitive performance of allelic groups of COMTVal158Met polymorphism. Met carriers (gray boxes) performed better in mental flexibility measured by (A) SFWGT (Switching strategy; p < 0.005; two way ANOVA) and had worse parental reports in two ABAS-II subscales: (B) ABAS-Self-Direction (p < 0.041; two way ANOVA) and (C) ABAS-Social Skills (p < 0.017; two way ANOVA), and also in the (D) social scale of the DMR; DMR-SOS (p < 0.039; two way ANOVA) than Val homozygotes (white boxes). The boxplots show the median as well as the interquartile range. Dots indicate individual values.