Figure 4.

Circulating neutrophils in the hamster mucositis model. Groups of hamsters (n = 3 per group) were treated as described for Figure 1A. Whole blood was collected, and the number of circulating neutrophils was determined on days 0, 7, 9, and 11 (A). Neutrophils were evaluated on day 11 (B). , control; , 80 mg/kg 5-FU; , scratching with 80 mg/kg 5-FU; and , scratching with 80 mg/kg 5-FU and 250 mg/kg PLAG. Average values were calculated. The bars represent error ranges. Statistical significance was assessed using Student’s t-test.