Fig. 1.
Co-registration of FDG-PET and MRI. (A) Axial FLAIR image in a 19-year-old man with the right medial frontal focal cortical dysplasia (FCD). Abnormally thickened cortex is associated with blurred gray-white matter junction (arrows). (B, C) Co-registered FDG-PET images show focal glucose hypometabolism in the lesion (arrows). Co-registration of FDG-PET and MRI improves detection and identification of FCD. The patient became seizure free after lesionectomy. Histo-pathological diagnosis was FCD type 2b. (D) Coronal T2 weighted image shows no remarkable abnormalities in a 27-year-old woman with the left temporal lobe epilepsy. (E, F) Co-registered FDG-PET showed glucose hypometabolism in the left anterior temporal lobe. The patient underwent left anterior temporal lobectomy, followed by seizure freedom. Histo-pathologically no specific abnormality was identified in the hippocampus and temporal neocortex.