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| iv | po | ||
|---|---|---|---|
| t1/2 (h) | 1.3 | t1/2 (h) | 3.3 |
| MRT (h) | 1.1 | Cmax (μg/mL) | 0.017 |
| CL (mL/h/kg) | 2335.7 | Tmax (μg/mL) | 0.5 |
| Vd(ss)(mL/kg) | 2530.3 | AUC0–48 h (μg h/mL) | 0.107 |
| Fb (%) | 25.2 | ||
Compound 10 was administered to rats at 0.2 mg/kg, i.v., or 1 mg/kg, p.o. (n = 3).
F means bioavailability.
