Table 2.
The most enriched Gene Ontology (GO) terms within categories biological process and molecular function and KEGG pathways assigned to the 86 up- and 44 down-regulated genes in the liver of cows of the CLA group compared to the control group.
| Up-regulated in the CLA group | Down-regulated in the CLA group |
|---|---|
| GO terms | |
| S-methyltransferase activity | Exopeptidase activity |
| Ribonucleoprotein complex biogenesis | Cytokinesis after mitosis |
| Homocysteine S-methyltransferase activity | Cytokinesis during cell cycle |
| Methionine biosynthetic process | Protein serine/threonine kinase activity |
| Spliceosome assembly | Cytokinesis |
| Methionine metabolic process | Metallopeptidase activity |
| Sulfur amino acid biosynthetic process | Retina development in camera-type eye |
| Regulation of cellular protein metabolic process | Establishment of organelle localization |
| RNA binding | |
| Aspartate family amino acid biosynthetic process | |
| KEGG pathways | |
| One carbon pool by folate | T cell receptor signaling pathway |
| Histidine metabolism | Steroid hormone biosynthesis |
| Cysteine and methionine metabolism | B cell receptor signaling pathway |
| Drug metabolism | Natural killer cell mediated cytotoxicity |
| PPAR signaling pathway | Neurotrophin signaling pathway |
| Spliceosome | Endocytosis |
The GO terms were sorted by their enrichment P-values (EASE score) (top: lowest P-value, bottom: highest P-value) within the GO categories biological process and molecular function. Only GO terms with P-values < 0.05 are shown.