Table 5. Single and joint analyte analysis on the association between Riboflavin and FMN and OSCC and GCA.
| Site | Stratification | Model including riboflavin | Model including FMN | Model including (riboflavin + FMN) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Riboflavin | FMN | Riboflavin | FMN | ||||||||||
| β | HRa | 95% CI | β | HRa | 95% CI | β | HRa | 95% CI | β | HRa | 95% CI | ||
| OSCC | Overall | −0.06145 | 0.94 | 0.90 to 0.98 | 0.04936 | 1.05 | 0.98 to 1.12 | −0.07720 | 0.93 | 0.88 to 0.97 | 0.08037 | 1.08 | 1.01 to 1.16 |
| Factor B recipients | −0.05308 | 0.95 | 0.88 to 1.02 | 0.1123 | 1.12 | 1.02 to 1.23 | −0.07975 | 0.92 | 0.86 to 0.99 | 0.1421 | 1.15 | 1.04 to 1.28 | |
| Factor B non-recipients | −0.07031 | 0.93 | 0.88 to 0.99 | −0.00958 | 0.99 | 0.90 to 1.09 | −0.07830 | 0.92 | 0.87 to 0.99 | 0.02313 | 1.02 | 0.93 to 1.13 | |
| GCA | Overall | −0.03049 | 0.97 | 0.92 to 1.03 | 0.05572 | 1.06 | 0.97 to 1.15 | −0.04251 | 0.96 | 0.90 to 1.02 | 0.08883 | 1.09 | 1.00 to 1.20 |
| Factor B recipients | 0.001703 | 1.00 | 0.92 to 1.09 | 0.06574 | 1.07 | 0.94 to 1.21 | −0.01375 | 0.99 | 0.91 to 1.07 | 0.1027 | 1.11 | 0.97 to 1.26 | |
| Factor B non-recipients | −0.05729 | 0.94 | 0.87 to 1.03 | 0.02996 | 1.03 | 0.91 to 1.16 | −0.06492 | 0.94 | 0.86 to 1.02 | 0.05851 | 1.06 | 0.93 to 1.20 | |
aHRs and 95% CIs were calculated using models adjusted for age, sex, cigarette smoking, alcohol drinking, and BMI. Overall models were also adjusted for receipt of Factor B. Continuous HRs were scaled to one-half IQR, which was 4.22 nmol/L for riboflavin, and 4.71 nmol/L for FMN, respectively.