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. 2016 Sep 1;30(17):1943–1955. doi: 10.1101/gad.283499.116

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© 2016 Liu et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 3. — Deletion of SMO in fibroblasts enhances tumor cell growth and proliferation through EGFR. (A) Quantitation of tumor mass 5 wk after implantation (tumors images are shown below the graph). Bar, 5 mm. n = 5. Each dot represents one tumor, and the red dot corresponds to the image below the graph. (B) Images and quantitation of the percentage of p-Histone H3⁺ over total CK19⁺ cells treated with the indicated CM. n = 3. Error bars represent means ± SD. (C) Images and quantitation of the percentage of p-Histone H3⁺ over total CK19⁺ cells cotreated with the indicated CM and DMSO or erlotinib. Bar, 40 μm. n = 3. Error bars represent means ± SD. (*) P < 0.05; (***) P < 0.001; (ns) not significant.