Table 1. Comparison of placental morphological parameters.
Morphological parameters | Control mimic (n = 5) | miR-16 mimic (n = 5) | Control inhibitor (n = 5) | miR-16 inhibitor (n = 5) |
---|---|---|---|---|
Proportion of spongiotrophoblast | 0.206 ± 0.047 | 0.208 ± 0.021 | 0.205 ± 0.026 | 0.207 ± 0.028 |
Proportion of labyrinth | 0.788 ± 0.057 | 0.791 ± 0.066 | 0.781 ± 0.049 | 0.790 ± 0.061 |
Total volume of spongiotrophoblast (mm3) | 249 ± 78.6 | 148 ± 43.4* | 254 ± 68.8 | 343 ± 72.6# |
Total volume of labyrinth (mm3) | 609 ± 102 | 449 ± 78.1* | 599 ± 108 | 849 ± 126# |
Total volume of fetal capillaries (mm3) | 72.3 ± 15.6 | 41.6 ± 10.2* | 70.8 ± 14.3 | 102.7 ± 18.8# |
Exchange barrier (μm) | 2.02 ± 0.056 | 5.13 ± 0.176* | 1.98 ± 0.069 | 1.06 ± 0.044# |
*P < 0.05 vs. control mimic; #P < 0.05 vs. control inhibitor.