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. 2016 Oct 17;6:35539. doi: 10.1038/srep35539

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Copyright © 2016, The Author(s)

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(A) Half-life of tritium-labeled DHT following i.v. injection. n = 4–9 per group. **P < 0.01. (B) Half-life of tritium-labeled T following i.v. injection. n = 3–6 per group. *P < 0.05. (C) Half-life of tritium-labeled mibolerone following i.v. injection. n = 6–10 per group. (D) Testosterone concentrations at 8 or 60 minutes following i.v. T injection. n = 6–10 per group. **P < 0.01 compared to 8 minute timepoint in same genotype. (E) Concentration of E2 in bone homogenates. n = 4 per group. *P < 0.05. (F) Relative mRNA expression of mouse aromatase (Cyp19a1) in the bones (tibia and femur) of 24-week-old WT and SHBG-Tg male mice. n = 9–11 per group.