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. Author manuscript; available in PMC: 2016 Oct 17.
Published in final edited form as: Science. 2016 Aug 4;353(6304):aaf4238. doi: 10.1126/science.aaf4238

Fig. 2. Differentially expressed genes during differentiation from EMP to macrophage.

Fig. 2

(A) (upper panel) Developmental pseudotime diagram (q-value<0.05) showing down regulation of EMP-specific genes (differentially expressed compared to the macrophage and pMac cluster, p-value<0.05, FC>1.4) over the differentiation path from EMP to pMacs and macrophages. (lower panel) Similar plot depicting macrophage-specific genes significantly regulated over pseudotime (q-value<0.05) and differentially expressed compared to the EMP and pMac cluster (p-value<0.05, FC>1.4)). See Fig. S2G. (B) Heatmap representation of selected genes differentially regulated between EMPs vs. pMacs and EMPs vs. early macrophages in bulk RNA-seq analysis. Black boxes were drawn around those samples used for differential expression analysis. See also Table S1, S2.