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. Author manuscript; available in PMC: 2016 Oct 17.
Published in final edited form as: Lancet Glob Health. 2016 Aug 23;4(10):e744–e751. doi: 10.1016/S2214-109X(16)30150-4

Table 4.

Test characteristics of individual clinical signs for some dehydration (unshaded) and severe dehydration (shaded)

Sensitivity Specificity LR positive (95% CI) LR negative (95% CI) χ2 Reliability*
General appearance 0·95
 Restless or irritable (some dehydration) 0·81 0·67 2·4 (2·0−2·9) 0·28 (0·21−0·37) 117·38 ··
 Lethargic or unconscious (severe dehydration) 0·73 0·69 2·3 (1·9−2·9) 0·39 (0·27−0·58)   44·66 ··

Skin pinch 0·85
 Slow (some dehydration) 0·84 0·68 2·6 (2·2−3·2) 0·23 (0·17−0·31) 138·51 ··
 Very slow (severe dehydration) 0·40 0·88 3·3 (2·2−4·8) 0·68 (0·56−0·83)   34·33 ··

Tears 0·63
 Decreased (some dehydration) 0·83 0·47 1·6 (1·4−1·8) 0·36 (0·27−0·49)   52·17 ··
 Absent (severe dehydration) 0·29 0·90 2·8 (1·8−4·5) 0·79 (0·68−0·92)   18·51 ··

Respirations 0·77
 Normal (some dehydration) 0·67 0·81 3·5 (2·7−4·6) 0·41 (0·34−0·49) 115·76 ··
 Deep (severe dehydration) 0·36 0·92 4·2 (2·7−6·6) 0·70 (0·59−0·84)   41·43 ··

Eyes 0·67
 Sunken eyes (some dehydration) 0·95 0·26 1·3 (1·2−1·4) 0·20 (0·11–0·35)   41·78 ··
 Sunken eyes (severe dehydration) 0·59 0·82 3·2 (2·4−4·2) 0·51 (0·38−0·67)   53·44 ··

Thirst 0·19
 Drinks eagerly and thirsty (some dehydration) 0·93 0·21 1·2 (1·1−1·3) 0·34 (0·20−0·56)   20·25 ··
 Not able to drink or drinks poorly (severe dehydration) 0·13 0·96 3·4 (1·6−7·4) 0·91 (0·83−0·99)   10·40 ··

LR=likelihood ratio.

*

Reliability assessed by Cohen’s κ (weighted).