Table 3.
Cox regression analysis of CRP on all-cause and cardiovascular mortality according to the presence of hypertension
| CRP (mg/L) | n | Median CRP (mg/L) | No, of of death | Mortality per 1000 person-years | Multi-adjusted1 HR (95% CI) | p for interaction |
|---|---|---|---|---|---|---|
| All-cause mortality | ||||||
| Men | ||||||
| Hypertension (-) | 4796 | 0.79 | 323 | 10.4 | 1.15 (1.09, 1.20) | - |
| Hypertension (+) | 4066 | 1.01 | 326 | 12.1 | 1.11 (1.05, 1.17) | 0.32 |
| Women | ||||||
| Hypertension (-) | 8321 | 0.59 | 168 | 3.1 | 1.11 (1.02, 1.21) | - |
| Hypertension (+) | 6050 | 0.84 | 199 | 4.9 | 1.02 (0.94, 1.11) | 0.11 |
| Cardiovascular mortality | ||||||
| Men | ||||||
| Hypertension (-) | 4796 | 0.79 | 41 | 1.3 | 1.14 (0.98, 1.32) | - |
| Hypertension (+) | 4066 | 1.01 | 46 | 1.7 | 1.19 (1.04, 1.37) | 0.58 |
| Women | ||||||
| Hypertension (-) | 8321 | 0.59 | 31 | 0.6 | 1.10 (0.88, 1.38) | - |
| Hypertension (+) | 6050 | 0.84 | 47 | 1.2 | 1.13 (0.97, 1.31) | 0.83 |
CRP, C-reactive protein; HR, hazard ratio; CI, confidence interval.
1
Adjusted for age, rural region, body mass index, educational status, alcohol use, smoking status, regular exercise, presence of disease (diabetes and dyslipidemia), systolic blood pressure, diastolic blood pressure, fasting blood glucose, and concentrations of total cholesterol, triglycerides, and high-density lipoprotein cholesterol.