Table 2.
Characteristic | LTBI Treatment Regimen |
|||
---|---|---|---|---|
9 INH (n = 115) | 4 RIF (n = 256) | 3HP (n = 53) | P Value | |
Mean age, years (SD) | 38.3 (12.3) | 43.0 (12.2) | 41.2 (16.0) | |
Mean weight, lbs (SD) | 172.2 | 186.8 | 161.4 | |
Male | 82 (71) | 167 (65) | 26 (49) | .02 |
Race | .02 | |||
Black | 83 (72) | 204 (80) | 40 (76) | |
Hispanic | 16 (14) | 30 (12) | 4 (8) | |
Asian | 6 (5) | 15 (6) | 8 (15) | |
White | 10 (9) | 7 (3) | 1 (2) | |
Foreign born | 35 (30) | 87 (34) | 16 (30) | .74 |
Non-English speaking | 11 (10) | 23 (9) | 4 (8) | .92 |
Married | 15 (13) | 55 (22) | 13 (25) | .10 |
Employed | 21 (18) | 71 (28) | 22 (42) | <.01 |
Stable housing | 96 (84) | 144 (56) | 49 (93) | <.01 |
HIV positive | 51 (44) | 12 (5) | 1 (2) | <.01 |
Diabetes | 10 (9) | 20 (8) | 1 (2) | .26 |
Psychiatric illness | 9 (8) | 8 (3) | 1 (2) | .07 |
Alcohol use | 32 (28) | 83 (32) | 26 (49) | .02 |
Tobacco use | 37 (32) | 70 (27) | 15 (28) | .64 |
Illicit drug use | 14 (12) | 21 (8) | 5 (9) | .48 |
Contact to active TB case | 24 (21) | 61 (24) | 21 (40) | .03 |
Abbreviations: HIV, human immunodeficiency virus; INH, isoniazid; lbs, pounds; LTBI, latent tuberculosis infection; RIF, rifampin; SD, standard deviation; TB, tuberculosis; 3HP, once-weekly, 3-month course of rifapentine plus isoniazid regimen.
a Values in parentheses refer to percentage unless otherwise noted.