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. Author manuscript; available in PMC: 2016 Oct 17.
Published in final edited form as: J Am Chem Soc. 2015 Aug 13;137(33):10480–10483. doi: 10.1021/jacs.5b06466

Table 3.

Scope of α-chloronitriles.a

graphic file with name nihms821011f5.jpg
a

Reaction conducted on 0.2 mmol scale. Isolated yields are provided; ee is determined by SFC using chiral stationary phase. Values in parentheses are yield and ee following a single recrystallization of the product.

b

2.0 equiv heteroaryl iodide used.

c

1 equiv NaBF4 added.