Table 4.
Intra-cluster correlations (ICCs) for plasma lipid levels by site of MDH enrollment.
| Outcome | % or mean (SD) | n/N or N | Sites | ICC (95% CI) |
|---|---|---|---|---|
| Dyslipidemiaa | ||||
| Prevalence at Enrollment | 45% | 17,093/38,046 | 26 | 0.0152 (0.0069, 0.0330) |
| Prevalence at 6 mo. | 44% | 3654/8290 | 21 | 0.0057 (0.0018, 0.0181) |
| Prevalence at 12 mo. | 43% | 3066/7074 | 16 | 0.0091 (0.0032, 0.0254) |
| Prevalence at 24 mo. | 47% | 2468/5215 | 17 | 0.0141 (0.0056, 0.0353) |
| Triglycerides (mg/dL) | ||||
| Value at enrollment | 134 (86) | 36,504 | 26 | 0.0107 (0.0044, 0.0257) |
| Change from enrollment to 6 mo. | −10 (90) | 4801 | 15 | 0.0025 (0.0004, 0.0141) |
| Change from enrollment to 12 mo. | −8 (96) | 3916 | 11 | 0.0022 (0.0003, 0.0169) |
| Change from enrollment to 24 mo. | 3 (104) | 2868 | 13 | 0.0047 (0.0011, 0.0196) |
| High Triglycerides (>150 mg/dL) | ||||
| Prevalence at Enrollment | 30% | 10,796/36,476 | 24 | 0.0072 (0.0030, 0.0174) |
| Prevalence at 6 mo. | 20% | 1622/7945 | 16 | 0.0049 (0.0015, 0.0159) |
| Prevalence at 12 mo. | 20% | 1375/6754 | 12 | 0.0083 (0.0028, 0.0241) |
| Prevalence at 24 mo. | 24% | 1182/4982 | 14 | 0.0131 (0.0045, 0.0375) |
| Total Cholesterol (mg/dL) | ||||
| Value at enrollment | 150 (63) | 37,436 | 26 | 0.0070 (0.0027, 0.0180) |
| Change from enrollment to 6 mo. | 14 (70) | 4980 | 15 | 0.0066 (0.0022, 0.0201) |
| Change from enrollment to 12 mo. | 19 (70) | 4090 | 11 | 0.0099 (0.0029, 0.0334) |
| Change from enrollment to 24 mo. | 17 (71) | 3034 | 13 | 0.0151 (0.0048, 0.0467) |
| High Total Cholesterol (>200 mg/dL) | ||||
| Prevalence at Enrollment | 15% | 5554/37,324 | 21 | 0.0039 (0.0012, 0.0126) |
| Prevalence at 6 mo. | 19% | 1552/8063 | 14 | 0.0007 (0.0001, 0.0081) |
| Prevalence at 12 mo. | 22% | 1537/6997 | 15 | 0.0011 (0.0001, 0.0107) |
| Prevalence at 24 mo. | 25% | 1273/5136 | 14 | 0 |
| LDL (mg/dL) | ||||
| Value at enrollment | 88 (44) | 8999 | 20 | 0.0147 (0.0057, 0.0371) |
| Change from enrollment to 6 mo. | 1 (34) | 1409 | 9 | 0.0121 (0.0031, 0.0455) |
| Change from enrollment to 12 mo. | 4 (35) | 949 | 8 | 0.0046 (0.0002, 0.0800) |
| Change from enrollment to 24 mo. | 3 (51) | 567 | 7 | 0.0173 (0.0016, 0.1649) |
| High LDL (>130 mg/dL) | ||||
| Prevalence at Enrollment | 11% | 1014/8802 | 11 | 0.0075 (0.0026, 0.0220) |
| Prevalence at 6 mo. | 13% | 500/3767 | 9 | 0.0025 (0.0004, 0.0138) |
| Prevalence at 12 mo. | 15% | 537/3638 | 10 | 0 |
| Prevalence at 24 mo. | 16% | 430/2636 | 10 | 0 |
| HDL (mg/dL) | ||||
| Value at enrollment | 36 (18) | 9061 | 20 | 0.0161 (0.0058, 0.0439) |
| Change from enrollment to 6 mo. | 14 (20) | 1463 | 9 | 0.0029 (0.0003, 0.0296) |
| Change from enrollment to 12 mo. | 17 (20) | 1020 | 8 | 0.0121 (0.0022, 0.0647) |
| Change from enrollment to 24 mo. | 12 (28) | 589 | 7 | 0.0066 (0.0003, 0.1438) |
| Low HDL (<40 mg/dL) | ||||
| Prevalence at Enrollment | 64% | 5804/9069 | 21 | 0.0207 (0.0067, 0.0622) |
| Prevalence at 6 mo. | 34% | 1367/3963 | 13 | 0.0041 (0.0010, 0.0168) |
| Prevalence at 12 mo. | 26% | 975/3711 | 9 | 0.0043 (0.0010, 0.0188) |
| Prevalence at 24 mo. | 29% | 775/2696 | 10 | 0.0072 (0.0019, 0.0273) |
a
TG ≥ 150 mg/dL, or TC ≥ 200 mg/dL, or LDL-c≥130 mg/dL, or HDL-c<40 mg/dL.