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. 2016 Nov;22(11):1771–1784. doi: 10.1261/rna.056531.116

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© 2016 Clark et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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FIGURE 1. — Methylations in human tRNA and rRNA investigated in this study. (A) Chemical structure of the six modifications where the methyl group is shown in red. The presence of each modification in tRNA and/or rRNA is listed beneath each base. (B) Schematic tRNA cloverleaf structure where the methylations for nuclear-encoded (left) and mitochondrial-encoded (right) tRNAs investigated in this work are located.