Table 2.
Unit costs Xpert MTB/RIF: top‐down and bottom‐up costs per test processed by input type, study arm and observation ($US2013)
| Start‐up stages of implementation (~3 months of implementationa) | Early stages of implementation (~3–6 months of implementationa) | Medium term stages of implementation (~12 months of implementationa) | ||||
|---|---|---|---|---|---|---|
| Time period | Control (observation 2) | Intervention (observation 1) | Intervention (observation 2) | |||
| Top down‐method | n = 5 | n = 10 | n = 9 | |||
| Mean | Range | Mean | Range | Mean | Range | |
| Overheads | $0.3 | ($0.1; $0.6) | $3.6 | ($0.2; $29.4) | $0.7 | ($0.2; $1.7) |
| Transport | $0.5 | ($0.1; $1.0) | $0.8 | ($0.1; $2.9) | $0.9 | ($0.1; $2.9) |
| Building space | $0.3 | ($0.1; $1.2) | $1.2 | ($0.2; $6.4) | $0.7 | ($0.2; $2.1) |
| Equipment | $35.2 | ($0.6; $76.9) | $1.3 | ($1.0; $1.7) | $1.6 | ($0.9; $3.4) |
| Staff | $10.0 | ($2.2; $20.5) | $2.7 | ($0.5; $13.5) | $1.5 | ($0.1; $2.3) |
| Reagents and chemicals | $10.9 | ($9.8; $13.8) | $15.3 | ($10.3; $39.7) | $12.5 | ($9.7; $17.4) |
| Calibration | $1.9 | ($0.4; $4.1) | $0.1 | ($0.1; $0.7) | $0.1 | ($0.1; $0.1) |
| Training Xpert MTB/RIF specific | $5.8 | ($1.1; $14.1) | $0.5 | ($0.2; $2.1) | $0.2 | ($0.2; $0.5) |
| Consumables | $0.3 | ($0.1; $0.4) | $1.5 | ($0.0; $12.4) | $0.3 | ($0.0; $1.3) |
| Above service‐level costs Xpert MTB/RIF | $3.2 | ($0.1; $11.0) | $1.4 | ($0.7; $3.6) | $1.2 | ($0.7; $3.1) |
| Mean unit cost for each Xpert MTB/RIF observation | $68.4 (SD, $45.5) | $28.4 (SD, $28.0) | $19.7 (SD, $3.5) | |||
| Mean top down unit cost for Xpert MTB/RIF | $33.5 (SD, $32.0) | |||||
| Bottom‐up method | n = 5 | n = 10 | n = 6 | |||
| Mean | Range | Mean | Range | Mean | Range | |
| Overheads | $0.3 | ($0.0; $1.0) | $0.4 | ($0.1; $0.9) | $0.3 | ($0.1; $0.6) |
| Transport | $0.4 | ($0.1; $1.0) | $0.8 | ($0.1; $2.9) | $1.1 | ($0.1; $2.9) |
| Building space | $0.2 | ($0.1; $0.5) | $0.2 | ($0.0; $0.4) | $0.2 | ($0.0; $0.8) |
| Equipment | $1.6 | ($0.2; $3.3) | $0.5 | ($0.0; $0.9) | $0.8 | ($0.3; $1.6) |
| Staff | $1.0 | ($0.3; $1.7) | $0.9 | ($0.1; $4.1) | $0.7 | ($0.1; $1.4) |
| Reagents and chemicals | $9.7 | ($9.7; $9.7) | $9.7 | ($9.7; $9.7) | $9.7 | ($9.7; $9.7) |
| Calibration | $1.9 | ($0.4; $4.1) | $0.1 | ($0.1; $0.7) | $0.1 | ($0.1; $0.1) |
| Training Xpert MTB/RIF specific | $5.8 | ($1.1; $14.1) | $0.5 | ($0.2; $2.1) | $0.2 | ($0.2; $0.3) |
| Consumables | $0.2 | ($0.1; $0.3) | $0.1 | ($0.0; $0.3) | $0.1 | ($0.0; $0.4) |
| Above service‐level costs Xpert MTB/RIF | $3.2 | ($0.1; $11.0) | $1.4 | ($0.7; $3.6) | $1.4 | ($0.7; $3.1) |
| Mean unit cost for each Xpert MTB/RIF observation | $24.3 (SD, $9.2) | $14.6 (SD, $2.0) | $14.6 (SD, $1.8) | |||
| Mean bottom‐up unit cost for Xpert MTB/RIF | $16.9 (SD, $6.1) | |||||
a
After the last laboratory implemented Xpert MTB/RIF.