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. 2016 Oct 11;8:363–371. doi: 10.2147/CLEP.S116160

Table 2.

Person-level agreement between self-report in interview and drug use calculated from prescription register data with PRE2DUP modeling method in the GeMS Study

Drug class or drug name and ATC code Interview as a standard
Register as standard
Kappa (95% CI)
Number of users based on interview Number of users in both Proportion found in register data Number of users based on register Proportion found in the interview
Alimentary tract and metabolism
Proton pump inhibitors, A02BC 50 40 80% 50 80% 0.78 (0.69–0.87)
Antidiabetics, A10 63 61 97% 61 100% 0.98 (0.96–1.00)
Insulins, A10A 18 18 100% 18 100% 1.00 (1.00–1.00)
Oral antidiabetics, A10B 55 52 95% 52 100% 0.97 (0.93–1.00)
Blood and blood forming organs
Antithrombotic drugs, B01A 154 143 93% 149 96% 0.92 (0.89–0.96)
Cardiovascular system
Digitalis, C01A 37 35 95% 38 92% 0.93 (0.87–0.99)
Organic nitrates, C01DA 240 195 81% 199 98% 0.82 (0.77–0.87)
Diuretics, C03 196 182 93% 196 93% 0.89 (0.85–0.93)
Beta-blocking agents, C07 353 342 97% 350 98% 0.93 (0.90–0.96)
Calcium channel blockers, C08 164 153 93% 169 91% 0.89 (0.84–0.93)
Agents acting on the renin- angiotensin system, C09 227 223 98% 240 93% 0.92 (0.89–0.96)
Lipid-modifying agents, C10 214 204 95% 208 98% 0.95 (0.92–0.98)
Genitourinary system and sex hormones
Drugs for urinary incontinence, G04BD 20 15 75% 17 88% 0.81 (0.66–0.95)
Drugs for benign prostatic hypertrophy, G04C 47 46 98% 50 92% 0.94 (0.90–0.99)
Systemic hormonal preparations
Levothyroxine, H03AA01 60 56 93% 56 100% 0.96 (0.92–1.00)
Musculoskeletal system
NSAIDs, M01A 95 40 42% 64 63% 0.43 (0.32–0.53)
Allopurinol, M04AA01 34 30 88% 32 94% 0.90 (0.83–0.98)
Drugs for treatment of bone diseases/bisphosphonates, M05 62 57 92% 63 91% 0.90 (0.84–0.96)
Nervous system
Opioids, N02A 16 9 56% 10 90% 0.69 (0.48–0.89)
Paracetamol, N02BE01 214 30 14% 36 83% 0.15 (0.10–0.21)
Antipsychotics, N05A 34 30 88% 32 94% 0.90 (0.83–0.98)
Benzodiazepines and related drugs, N05BA, N05CD, N05CF 189 134 71% 150 89% 0.70 (0.64–0.77)
Antidepressants, N06A 70 53 76% 57 93% 0.81 (0.74–0.89)
Antidementia drugs, N06D 65 59 91% 59 100% 0.95 (0.90–0.99)
Respiratory system
Drugs for obstructive airway diseases, R03 68 55 81% 61 90% 0.83 (0.76–0.91)
Adrenergics, inhalations, R03A 55 35 64% 41 85% 0.71 (0.60–0.82)
Other drugs for obstructive airway diseases, inhalations, R03B 39 33 85% 37 89% 0.86 (0.77–0.95)
Sensory organs
Antiglaucoma preparations, S01E 44 43 98% 50 86% 0.91 (0.84–0.97)

Abbreviations: ATC, Anatomical Therapeutic Chemical; CI, confidence interval; NSAIDs, non-steroidal anti-inflammatory drugs.