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. 2016 Feb 2;5(4):296–305. doi: 10.1002/cpdd.240

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© 2016, The Authors. Clinical Pharmacology in Drug Development Published by Wiley Periodicals, Inc. on behalf of The American College of Clinical Pharmacology

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Plasma concentrations of PTC299 by dose. (A) Twice‐daily dosing of PTC299 for 7 days. (B) Three‐times‐daily dosing of PTC299 for 7 days. (C) Plasma concentrations of PTC299 by dose after cessation of twice‐daily dosing. A value of zero was used for calculating mean values if the measured concentration was below the lower limit of quantification.