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Composition of the DPI products containing an optimal concentration of excipients
| No | CIP (g) | LEU (g) | PVA (g) | CD (g) | Solvent (mL) |
|---|---|---|---|---|---|
| 1 | 1 | – | – | – | 50 |
| 2 | 1 | – | 0.2 | – | 50 |
| 3 | 1 | – | – | 0.9 | 50 |
| 4 | 1 | 0.4 | – | – | 50 |
| 5 | 1 | 0.4 | 0.2 | 0.9 | 50 |
Abbreviations: DPI, dry powder inhalation; PVA, polyvinyl alcohol; CIP, ciprofloxacin hydrochloride; LEU, l-leucine; CD, cyclodextrin.
