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. 2016 Oct 11;11:5257–5276. doi: 10.2147/IJN.S112030

Figure 10.

Figure 10

Schematic model of ROS-dependent MAPK/Bcl-2 and PI3K/Akt/mTOR signaling mediated cross talk between autophagy and apoptosis involved in endothelial injury triggered by SiNPs.

Abbreviations: ROS, reactive oxygen species; SiNPs, silica nanoparticles; NAC, N-acetylcysteine.