Fig. 3.
Assessment of fibrosis in hearts. (a) Representative Picro-sirius red staining for collagen deposition (red color) and polarization microscopic pictures for collagen-1 (yellow color) and collagen-3 (green color) from capns1-ko mice and their wild-type littermates fed a HFD or ND. (b) Total collagen deposition. (c) Collagen-1 deposition. (d) Collagen-3 deposition. The quantification of collagen-1 mRNA (e) and collagen-3 mRNA (f). Data are mean ± SD, n = 6. *P < 0.05 vs ND + WT and †P < 0.05 vs HFD + WT.