Table 1. Characteristics of studies included in the meta-analysis.
| First author [reference] | Country/Region | Ethnicity | Genotyping method | Cases (age) | Controls (age) | Design of Experiment | NOS score |
|---|---|---|---|---|---|---|---|
| Kim (2005) (19) | Korea | Asian | PCR-RFLP | N=153 (62.9±11.8 years) | N=153 (60.7±11.8 years) | Hospital-based | 6 |
| Karahalil (2006) (20) | Turkey | Caucasian | PCR-RFLP | N=100 (mean age 59.87 years) | N=100 (mean age 59.33 years) | Hospital-based | 6 |
| Huang (2007) (21) | USA | Caucasian | Taqman | N=696 (63.94±11.17 years) | N=629 (62.77±10.50 years) | Hospital-based | 7 |
| Figueroa (2007) (22) | Spain | Caucasian | Taqman | N=1150 (66±10 years) | N=1149 (65±10 years) | Hospital-based | 6 |
| Arizono (2008) (23) | Japan | Asian | PCR-RFLP | N=251 (68.2±11.2 years) | N=251 (68.1±11.7 years) | Population-based | 6 |
| Narter (2009) (10) | Turkey | Caucasian | PCR-RFLP | N=83 (63.43±11.74 years) | N=45 (59.98±9.71 years) | Hospital-based | 7 |
| Wang (2011) (24) | Taiwan | Asian | PCR-RFLP | N=460 (62.7±10.9 years) | N=540 (61.9±11.0 years) | Hospital-based | 7 |
| Mittal (2011) (30) | India | Asian | ARMS-PCR | N=212 (59.6±12.4 years) | N=250 (58.8±10.8 years) | Hospital-based | 6 |
| Ma (2012) (27) | China | Asian | TaqMan | N=1050 (65±5 years) | N=1404 (65±5 years) | Hospital-based | 6 |
| Ramaniuk (2014) (28) | Belarus | Caucasian | PCR-RFLP | N=336 (67.0±10.7 years) | N=370 (64.5±13.5 years) | Hospital-based | 8 |