Table 2.

Analysis of prognostic factors of HLH

Risk factors	β	Standard error	χ2	OR	95% Confidence interval	P-value
Age <2 years	2.905	8.515	7.636	18.661	1.562–197.781	0.007
N <1.0×109/L	−0.836	0.202	1.244	0.424	0.021–4.881	0.288
Hb <60 g/L	1.775	2.266	0.715	5.891	0.612–60.271	0.395
Plt <50 g/L	0.911	1.164	2.060	2.491	0.214–23.115	0.142
LDH >2,000 U/L	3.335	13.881	8.891	29.771	2.681–317.114	0.003
AST >400 U/L	2.603	6.337	2.249	13.771	1.298–133.141	0.133
ALT >400 U/L	2.515	5.661	1.441	12.361	1.017–130.712	0.230
EBV infection	2.055	3.660	1.958	10.123	0.612–71.124	0.163
CMV infection	1.061	1.335	0.615	7.821	0.216–38.218	0.411
Bilirubin >2 mg/mL	3.066	11.315	10.331	19.145	1.225–113.512	0.013

Abbreviations: HLH, hemophagocytic lymphohistiocytosis; N, neutrophil; Hb, hemoglobin; Plt, platelet; LDH, lactate dehydrogenase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; EBV, Epstein–Barr virus; CMV, cytomegalovirus; OR, odds ratio.