Fig. 4.

Correlation of striatal anticipation responses with impulsivity. A: Left panel: Controls exhibited a positive correlation between the ventral striatal ([x y z] = [9 8 1]) gain anticipation response and impulsivity (as reflected by the BIS-11 sum score; π = 0.55, p = 0.031). Right panel: In the patients, this correlation was also positive, but failed to reach statistical significance (π = 0.23; p = 0.671). B: While controls showed a significant positive correlation between the striatal loss anticipation response and the BIS-11 sum score (left panel; π = 0.55, p = 0.018), the correlation was significantly negative in patients (right panel; π = − 0.59; p = 0.012). Note: One control subject had a beta value of > 500, resulting in an outlier that is not displayed in the figure.