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. Author manuscript; available in PMC: 2016 Oct 17.
Published in final edited form as: ACS Chem Biol. 2015 Dec 2;11(3):632–642. doi: 10.1021/acschembio.5b00841

Figure 2.

Figure 2

MOF/MSL1 complex. (a) Uncomplexed MOF (green) overlaid with MOF/MSL1 complex (MOF in marine, MSL470540 in gold, AcCoA in orange) (PDB codes: 2Y0M and 2GIV). (b) Zoomed in view of select interactions between the MOF HAT domain and MSL1. Zinc atom represented as navy sphere. (c) Linear representation of select interactions between the MOF HAT domain and MSL1 PEHE region. Dashed lines represent interactions. Domain and secondary structure naming correspond to primary texts. Asterisks denote residues that are inserted into hydrophobic pockets of their binding partner.