Table 4.

Dietary phytochemicals and changes in miRNA levels.

Dietary Agent	Disease Type	miRNA	Concentration	Ref.
Apigenin	Lung cancer cells	miR138, miR-125a-5p	25–100μM	230
	Neuroblastoma cells	miR-138	100 μM	229
Curcumin	Bladder cancer cells	miR-203	1–20 μM	231
	Lung cancer cells	miR-320, miR-26a, let-7i, miR-130a, mir-16, miR-125b,miR-23a, miR-27b, miR-155, miR-625, miR-576-3p, miR-186, miR-9	10–50 μM	232
	Leukemia	miR-15a, miR-16-1	5–20 μM	233
	Pancreatic cancer cells	miR-103, miR-140, miR-146b, miR-148, miR-15b,miR-181a, miR-181b, miR-181d, miR-195, miR-196a,miR-199a, miR-19a,miR-204, miR-20a, miR-21, miR-22miR-23a,b, miR-24, miR-25, miR-26a, miR-27a, miR-34a,miR-374, miR-510, miR-7, miR-92, miR-93, miR-98	10 μmol/L	234
EGCG	Neuroblastoma cells	miR-92, miR-93,miR 106b, miR-34a, miR-99a	25–100 μM	228
	Hepatocellular carcinoma cells	miR-467b, miR-487b, miR-197, miR-805, miR-374, let-7f, miR-350, miR-24-1, miR-137, miR-335-3p, let-7a, miR-222, miR-26b, miR-30c-1, let-7d, miR-98, miR-30c, miR-30b, miR-32, miR-674, miR-532-5p, let-7g, miR-18a, miR-192, miR-302d, miR-30b, miR-802, let-7e,miR-322, miR-720, miR-146b, miR-340-3p, miR-185, miR-425, miR-10a, miR-126-5p, miR-101a, miR-30e, let-7c, miR-141, miR-33, miR-29a, miR-199b, miR-450a-5p, miR-21, miR-23a, miR-101b, miR-148a, miR-193, miR-23b, miR-107, miR-140, miR-551b, miR-466c-5p, miR-106a, miR-590-3p, miR-875-3p, miR-224, miR-292-5p, miR-678, miR-469, let-7b, miR-463miR-574-3p, miR-201, miR-290-3p, miR-181a, miR-302a, miR-429, miR-133a, miR-190b, miR-710, miR-135b, miR-296-5p, miR-191, miR-188-5p, miR-298, miR-181a-1, miR-466g, miR-26b, miR-466f-3p, miR-29b, miR-1224, miR-291b-5p, miR-324-5p, miR-486, miR-128, miR-450b-3p, miR-135a, miR-294, miR-671-5p, miR-878-3p, miR-801, miR-370, miR-1, miR-494, miR-133b	100 μM	235
	Lung carcinoma	let-7c, miR210	100 μM	235
	Pancreatic cancer cells	let-7c	100 μM	235
	Colon carcinoma cells	miR-27a, miR-20A, miR-17-5P, miR-21	5–30 μM	236
Genistein	Ovarian cancer cells	miR-100, miR-122a, miR-125b, miR-126, miR-135, miR-135b, miR-136, miR-137, miR-141, miR-152,miR-190, miR-196a, miR-196b, miR-204, miR-205, miR-206, miR-217, miR-22, miR-296, miR-30a-3p, miR-30a-5p, miR-331, miR-335, miR-342, miR-362, miR-449b, miR-454, miR-497, miR-500, miR-501, miR-503, miR-515, miR-517c, miR-532, miR-565, miR-578, miR-584, miR-585, miR-590, miR-595, miR-625, miR-647, miR-7, miR-765, miR-766	5 μM	136
	Pancreatic cancer cells	miR-200	50 μM	137
Indole-3 carbinol Diindolylmethane	Breast cancer cells	miR34a	25 μM	137
	Prostate cancer cells	miR34a	10 μM	238
		miR-21	30–60 μM for cells 5mg/kg (mice)	237
	Mouse lung tumors	miR-21, mir-31, miR-130a, miR-146b and miR-377	100–150 μM	239
Lycopene	Hepa 1–6 cells (hepatic cells)	miR-21	0.05% (fed orally to mice)	240
Diallyl disulphide	Endothelial progenitor cells	miR-221	0–10 μM (10mg/kg/day)	241
	Breast Cancer	miR34a	25–400 μM	242
Resveratrol	Prostate cancer cells from lymph node	miR-1224-5p, miR-1228, miR-1231, miR-1246, miR-1260, miR-1267, miR-1268, miR-129, miR-1290, miR-1308, miR-1469, miR-149, miR-150, miR-152, miR-15a, miR-17, miR-1825, miR-185, miR-18b, miR-1908, miR-1915, miR-197, miR-1972, miR-1973, miR-1974, miR-1975, miR-1977, miR-1979, miR-20a, miR-20b, miR-24, miR-296-5p, miR-483-5p, miR-513a-5p, miR-548q, miR-572, miR-575, miR-612, miR-638, miR-654-5p, miR-659, miR-671-5p, miR-7, miR-762, miR-764, miR-874, miR-92b, miR-939	50 μM	243
	Prostate cancer cells	miR-101, miR-106a, miR-106b, miR-1274b, miR-136, miR-141, miR-145, miR-17, miR-182, miR-1826, miR-200b, miR-200c, miR-20a, miR-20b, miR-21, miR-214, miR-221, miR-222, miR-302c, miR-375, miR-378, miR-720, miR-768-3, miR-93	5–100 μM	244
	Colorectal cancer cells	miR-1, miR-100-1/2, miR-102, miR-103-1, miR-103-2, miR-146a, miR-146b-5p, miR-16-0, miR-17, miR-181a2, miR-194-2, miR-196a1, miR-205, miR-206, miR-21, miR-23a, miR-23b, miR-25, miR-26a, miR-29c, miR-30a-3p, miR-30c-1, miR-30d, miR-30e-5p, miR-323, miR-340, miR-363-5p, miR-424, miR-494, miR-497, miR-560, miR-560, miR-565, miR-565, miR-572, miR-574, miR-594, miR-615, miR-622, miR-629, miR-631, miR-638, miR-639, miR-657, miR-659, miR-663, miR-801, miR-92a-2	50 μM	245
Luteolin	Prostate cancer cells	miR-630	0–10 μM	246
	Gastric cancer cells	miR-34a	5–50 μM	247
Phenethyl isothiocyanate	Prostate cancer cells	miR-141	0–20 μM	248