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. Author manuscript; available in PMC: 2017 Oct 5.
Published in final edited form as: Cells Tissues Organs. 2016 Oct 5;202(1-2):116–135. doi: 10.1159/000446621

Figure 1.

Figure 1

Implantation of a HAMC hydrogel loaded with NT-3 releasing PLGA nanoparticles promoted axonal growth into spinal compression injury lesion site in adult rats. B) The compression lesion site was significantly smaller after implantation of NT-3 releasing HAMC hydrogel due to increased axonal regeneration. C) Enlarged view of boxed area in B which shows NF200 positive axons growing into lesion site. D) Compression lesion site in animals that received NT-3 free HAMC hydrogel did not show increase in axonal extension compare to SCI control group (E). This figure was reproduced from Donaghue et al. with permission from the Royal Society of Chemistry [Elliott Donaghue et al., 2015a].