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. Author manuscript; available in PMC: 2017 Oct 5.
Published in final edited form as: Cells Tissues Organs. 2016 Oct 5;202(1-2):116–135. doi: 10.1159/000446621

Figure 3.

Figure 3

Aligned electrospun PLLA fiber scaffolds implanted into complete transection model of SCI in adult rats promote axonal regeneration across lesion site. A, D, G) PLLA films implanted into SCI transection lesion did not allow for axonal extension into lesion site over the course of 4 weeks. B, E, H) Random fiber conduits promoted marginal axonal extension, but significantly less than aligned fiber conduits in C, F, and I. 4 weeks after implantation of aligned fiber conduits, all animals exhibited axonal regeneration from the rostral spinal cord of at least 1.5 mm. This figure was reproduced from Hurtado et al. with permission from Elsevier [Hurtado et al., 2011].