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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Drug Discov Today. 2016 Jun 14;21(10):1609–1619. doi: 10.1016/j.drudis.2016.06.004

Figure 3.

Figure 3

[QA3] Potential routes to drug biotransformation. Specific pharmacokinetic processes trigger subsequent pharmacodynamics processes that determine many important aspects of drug therapy. Biotransformation events are not limited to the liver and gut, because they are also mediated by drug-metabolizing enzymes expressed in regions of the brain.