Table II.

HLA-C genotypes and clinical features of the 28 participating psoriasis patients

	HLA-Cw*0602
	Homozygous	Heterozygous	Negative	P value*
Number, n (%)	4 (14)	17 (61)	7 (25)
Sore throat-induced psoriasis onset,† n (%)	4 (100)	5 (29)	2 (29)	.007**
Sore throat per year,† mean n ± SD	5.3 ± 3.5	3.9 ± 2.9	6.9 ± 3.6	.768
Strep-throat per lifetime,‡ mean n ± SD	3.5 ± 2.1	1.4 ± 1.5	1.1 ± 0.6	.038**
Streptococcal carriage,§ n (%)	3 (75)	11 (65)	3 (43)	.527
Cigarette Smoking, n (%)	4 (100)	5 (29)	3 (43)	.013**
Psoriasis family history, n (%)	4 (100)	14 (82)	5 (71)	.314

^*HLA-Cw*0602 homozygous patients compared to heterozygous and HLA-Cw*0602 negative patients.

^†As recalled by the patients.

^**Statistically significant.

^‡Streptococcal throat infections diagnosed by a physician, throat culture or strep test (rapid antigen detection test).

^§Cultured at the time of the tonsillectomy.