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Cartoon describing the secondary, tertiary and quaternary structures of MIF (1GD0, a and d), D-DT (1DPT, b and e), and the CD74 trimerization domain (1IIE, c and f). Atomic coordinates were retrieved from the Protein Data Bank (PDB) and ribbon-rendered using PyMol. Upper row shows views of the structures from the top. Lower row show a lateral view of the same homotrimers. Molecular image of CD74 is at a smaller scale to allow visualization of the unstructured random coils.
