Figure 6. Changes of histone H3 acetylation and methylation following CP and As treatment of hNPCs cultured under proliferation and differentiation conditions at 72 h post treatment.
Histone modifications at specific sites were quantified by western blotting following 72h treatment with CP or As (positive control) under proliferating or differentiating conditions. Plots show means and 95% confidence intervals. Statistical significances, * = p<0.05; ** = p<0.01, are based on a linear mixed effect model indicating significant dose response for each condition.