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Plasma PUFA metabolites influenced by placebo (OO) supplementation. A) LA (18:2, n-6) derived HODEs/oxo-octadecadienoic acids (OxoODEs) and epoxy-octadecenoic acids (EpOMEs)/ DiHOMEs). B) AA (20:4, n-6) derived COX-1 and 2 pathway prostanoids (PGE2 and TXB2) and CYP-pathway–derived epoxide vicinal diols (5,6-, 8,9-, 11,12-, and 14,15-DiHETrE). Value are means ± sem. *P < 0.05 vs. d 0 within the respective supplementation period.
