Table 2.

Multivariate Cox proportional hazard analysis of individual subscores in predicting 5-year transplant-free survival

Regressor	LogWorth	p value	Univariable score	RR (95 % CI)	p value	LogWorth	p value	Multivariable score	RR (95 % CI)	p value
(A) mCTP
Age	185.6	<0.0001		1.02 (1.02–1.03)		227.5	<0.0001		1.028 (1.026–1.030)	<0.0001
Gender	14.8	<0.0001	M	1.0 (ref.)		2.8	0.001	M	1.0 (ref.)
			F	0.65 (0.58–0.73)	<0.0001			F	0.83 (0.74–0.93)	0.001
Albumin	1186.8	<0.0001	1	1.0 (ref.)		714.4	<0.0001	1	1.0 (ref.)
			2	1.8 (1.7–1.9)	<0.0001			2	1.6 (1.6–1.7)	<0.0001
			3	4.1 (3.9–4.2)	<0.0001			3	3.2 (3.1–3.3)	<0.0001
Ascites	447.9	<0.0001	1	1.0 (ref.)		155.6	<0.0001	1	1.0 (ref.)
			2	2.0 (2.0–2.1)	<0.0001			2	1.5 (1.5–1.6)	0.0001
			3	4.9 (4.4–5.3)	<0.0001			3	2.5 (2.2–2.7)	<0.0001
Total bilirubin	577.7	<0.0001	1	1.0 (ref.)		144.4	<0.0001	1	1.0 (ref.)
			2	2.0 (1.9–2.2)	<0.0001			2	1.5 (1.4–1.6)	<0.0001
			3	3.9 (3.6–4.1)	<0.0001			3	2.1 (2.0–2.2)	<0.0001
Encephalopathy	378.4	<0.0001	1	1.0 (ref.)	<0.0001	55.02	<0.0001	1	1.0 (ref.)
			2	1.8 (1.7–1.9)				2	1.2 (1.1–1.3)	<0.0001
			3	4.0 (3.7–4.3)	<0.0001			3	1.8 (1.7–1.9)	<0.0001
INR	235.4	<0.0001	1	1.0 (ref.)	<0.0001	24.23	<0.0001	1	1.0 (ref.)
			2	2.1 (2.0–2.2)	<0.0001			2	1.3 (1.2–1.4)	<0.0001
			3	3.5 (2.5–4.6)				3	1.3 (1.0–1.8)	0.07
(B) mCTP-Cr
Age	185.6	<0.0001		1.02 (1.02–1.03)		266.7	<0.0001		1.03 (1.03–1.03)	<0.0001
Gender	14.8	<0.0001	M	1.0 (ref.)		2.4	0.003	M	1.0 (ref.)
			F	0.65 (0.58–0.73)	<0.0001			F	0.84 (0.75–0.94)	0.003
Albumin	1186.8	<0.0001	1	1.0 (ref.)	<0.0001	697.4	<0.0001	1	1.0 (ref.)	<0.0001
			2	1.8 (1.7–1.9)	<0.0001			2	1.6 (1.6–1.7)	<0.0001
			3	4.1 (3.9–4.2)				3	3.2 (3.0–3.3)	<0.0001
Ascites	447.9	<0.0001	1	1.0 (ref.)		146.1		1	1.0 (ref.)
			2	2.0 (2.0–2.1)	<0.0001			2	1.5 (1.5–1.6)	<0.0001
			3	4.9 (4.4–5.3)	<0.0001			3	2.3 (2.1–2.5)	<0.0001
Total bilirubin	606.9	<0.0001	1	1.0 (ref.)		178.6		1	1.0 (ref.)
			2	2.2 (2.1–2.3)	<0.0001		<0.0001	2	1.5 (1.4–1.6)	<0.0001
			3	4.6 (4.4–5.0)	<0.0001			3	2.2 (2.1–2.3)	<0.0001
Encephalopathy	378.4	<0.0001	1	1.0 (ref.)		55.2	<0.0001	1	1.0 (ref.)
			2	1.8 (1.7–1.9)	<0.0001			2	1.2 (1.2–1.3)	<0.0001
			3	4.0 (3.7–4.3)	<0.0001			3	1.8 (1.7–1.9)	<0.0001
Creatinine	172.1	<0.0001	1	1.0 (ref.)		98.9	<0.0001	1	1.0 (ref.)
			2	2.2 (2.1–2.4)	<0.0001			2	1.6 (1.5–1.7)	<0.0001
			3	2.7 (2.5–2.9)	<0.0001			3	2.1 (1.9–2.2)	<0.0001