Fig. 4.
a, b The effect of mild WRS and alendronate (300 mg/kg i.g.) alone and the combination of mild WRS and alendronate (300 mg/kg i.g.) with or without pretreatment with CORM-2 (5 mg/kg i.g.) or NaHS (5 mg/kg i.g.) on H2S production in gastric mucosa determined by CSE/CBS (a) or 3-MST (b) activity in gastric mucosa. Results are mean ± SEM of 4–6 rats per each group. Significant change (p < 0.05) as compared with the respective values in intact rats was indicated by asterisk. Cross indicates significant change (p < 0.05) comparing to the values obtained in vehicle-control gastric mucosa