Table 1.

Development of type 2 diabetes in male SD rats.

Parameters	Normal	Diabetic
Body weight (g)	326 ± 12.5	325 ± 5.6
Cardiac mass index (g/cm)	320 ± 9.0	307 ± 4.9
Fasting blood glucose (mmol/L)	8.0 ± 0.20	21.6 ± 0.71∗
Fasting plasma insulin (pmol/L)	175.7 ± 3.16	178.1 ± 2.90
HOMA score	4.2 ± 0.09	20.3 ± 3.31∗

Diabetic rats were provided with HFD and were given a single shot STZ (30 mg/Kg) intraperitoneally. Control rats were provided with standard diet and injected with equal amount of saline. All the rats were fasted overnight and body weight, cardiac mass index, fasting blood glucose, fasting plasma insulin, and the HOMA score were determined. Cardiac mass index = wet heart weight/tibia length, ^∗ p < 0.01 versus normal; n = 40 per group.